MeasureCorrelationx - modified MeasureCorrelation module to implement RWC coefficients

The following python module is an extension to the MeasureCorrelation module available for measurement within CellProfiler (Broad Institute) for measuring co-localization. This extended version now includes Overlap coefficient, Manders' coefficients (M1 and M2), Costes' automated threshold and Rank Weighted Co-localization coefficients (RWC1 and RWC2). 

     You can download the module here.

NOTE:

• Download and install CellProfiler (http://cellprofiler.org/download.shtml)
• To install the MeasureCorrelationx module, download the module to a folder.
• Open CellProfiler and point the "CellProfiler plugins directory" within the preferences option to the folder having the downloaded module.
• Restart CellProfiler and you should see MeasureCorrelationx under the available "Measurement" module.

Author: Vasanth R. Singan (VRSingan @ lbl.gov) 

Please cite our work:

Dual channel rank-based intensity weighting for quantitative co-localization of microscopy images

VR Singan, TR Jones, KM Curran, JC Simpson

BMC bioinformatics 12 (1), 407

Quantitative image analysis approaches for probing rab gtpase localization and function in mammalian cells

VR Singan, K Handzic, JC Simpson

Biochemical Society Transactions 40 (6), 1389

Implementation of the Rank-Weighted Co-localization (RWC) algorithm in multiple image analysis platforms for quantitative analysis of microscopy images

VR Singan, JC Simpson

Source Code for Biology and Medicine 11 (2)